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Lab. Invest. 76(3), p365-374 (1997)
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Protective role of dietary anti-oxidants in oxidative stress.
Oxidative Stress and Aging (Esd:R.G.Cutler, L.Packer, Bertram and A.Mori) p367-377, Birkhser Verlag Basel, Switzerland (1995)
2) Kasai H:
Analysis of a form of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis.
Mutat Res. 387(3):147-63.(1997)
3) J.Leinonen, T.Lehtimi, S.Toyokuni, K.Okada, T.Tanaka, H.Hiai, H.Ochi, P.Laippala, V.Rantalaiho, O.Wirta, A.Pasternack, and H.Alho:
New biomarker evidence of oxidative DNA damage in patients with non-insulin-dependent diabetes mellitus.
FEBS Lett. 417, p150-152 (1997)
4) M.Erhola, S.Toyokuni, K.Okada, T.Tanaka, H.Hiai, H.Ochi, K.Uchida, T.Osawa, M.M.Nieminen, H.Alho, and P.K-Lehtinen:
Biomarker evidence of DNA oxidation in lung cancer patients: association of urinary 8-hydroxy-2¡¦deoxyguanosine excretion with radiotherapy, chemotherapy, and response to treatment.
FEBS Lett. 409, p287-291 (1997)
5) H.Tsuboi, K.Kouda, H.Takeuchi, M.Takigawa, Y.Masamoto, M.Takeuchi, and H.Ochi:
8-Hydroxydeoxyguanosine in urine as an index of oxidative damage to DNA in the evaluation of atopic dermatitis.
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6) Y.Miyake, K.Yamamoto, N.Tsujihara, and T.Osawa:
Protective effects of lemon flavonoids on oxidative stress in diabetic rats.
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Sesamolin inhibits lipid peroxidation in rat liver and kidney.
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8) S.S.Kantha, S.Wada, H.Tanaka, M.Takeuchi, S.Watabe, and H.Ochi:
Carnosine sustains the retention of cell morphology in continuous fibroblast culture subjected to nutritional insult.
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9) S.S.Kantha, S.Wada, M.Takeuchi, S.Watabe, and H.Ochi:
A sensitive method to screen for hydroxyl radical scavenging activity in natural food extracts using competitive inhibition ELISA for 8-hydroxydeoxyguanosine.
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10) T.Arimoto, T.Yoshikawa, H.Takano and M.Kohno:
Generation of rective oxygen species and 8-hydroxy-2'-deoxyguanosine formation from diesel exhaust particles components in L1210 cells.
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11) M.D.Evans, M.S.Cooke, I.D.Podmore, Q.Zheng, K.E.Herbert, and J.Lunec:
Discrepancies in the measurement of UVC-induced 8-oxo-2'-deoxyguanosine: Implications for the analysis of oxidative DNA damage.
Biochem. Biophys. Res. Commun. 259, p374-378 (1999)
DNAÃæ¤Î8-OHdG¤ò¡¢HPLC-ECDË¡¤ÈELISAË¡¤Ç¬Äꤷ¤¿¾ì¹ç¡¢¹â¤¤Áê´ØÀ­¤ò¼¨¤¹¤³¤È¤¬Êó¹ð¤µ¤ì¤Æ¤¤¤Þ¤¹¡Êr2 =0.958¡Ë¡£
12) M.S.Cooke, M.D.Evans, I.D.Podmore, K.E.Herbert, N.Mistry, P.Mistry, P.T.Hickenbotham, A.Hussieni, H.R.Griffiths, and J.Lunec:
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14) M.S.Cooke, M.D.Evans, K.E.Herbert, and J.Lunec:
Urinary 8-oxo-2'-deoxyguanosine - source, significance and supplements.
Free Rad. Res. 32, p381-397 (2000)
15) T. Shimoike, T. Inoguchi, F. Umeda, H. Nawata, K. Kawano and H. Ochi:
The meaning of serum levels of advanced glycosylation end products in diabetic nephropathy.
Metabolism 49(8), p1030-1035 (2000)
16) W. Y. Fan, K. Ogusu, K. Kouda, H. Nakamura, T. Satoh, H. Ochi and H. Takeuchi:
Reduced oxidative DNA damage by vegetable juice intake: A controlled trial.
J. Physiol. Anthropol. 19(6), p287-289 (2000)
17) H.Ochi, M.Hashimoto, J.Kurashige:
Assessment of functional tea in human using oxidative stress profile technique.
Proceedings of 2001 International Conference on O-Cha (tea) Culture and Science (2001)
18) T. Kuragano, T. Kuno, C. Yamamoto, Y. Nagura, S. Takahashi and K. Kanmatsuse:
Oxidative stress on DNA in chronic renal failure: the influence of different hemodialysis membranes.
J. Artif. Organs 4, p320-325 (2001)
19) M.S.Cooke, M.D.Evans, R.M.Burd, K.Patel, A.Barnard, J.Lunec and P.E.Hutchinson:
Induction and excretion of ultraviolet-induced 8-oxo-2'deoxyguanosine and thymine dimmers in vivo: implications for PUVA.
J. Invest. Dermatol. 116(2), p281-285 (2001)
20) M.S.Cooke, M.D.Evans and J.Lunec:
DNA repair: insights from urinary lesion analysis.
Free Rad. Res. 36(9), p929-932 (2002)
21) M.S.Cooke, M.D.Evans, N.Mistry and J.Lunec:
Role of dietary antioxidants in the prevention of in vivo oxidative DNA damage.
Nutr. Res. Rev. 15, p19-41 (2002)
22) T. Matsubasa, T. Uchino, S. Karashima, Y. Kondo, K. Maruyama, M. Tanimura and F. Endo:
Oxidative stress in very low birth weight infants as measured by urinary 8-OHdG.
Free Rad. Res. 36(2), p189-193 (2002)
23) Y.Ibuki, T.Warashina, T.Noro and R.Goto:
Coexposure to benzo[a]pyrene plus ultraviolet A induces 8-oxo-7,8-dihydro-2¡¦deoxyguanosine formation in human skin fibroblasts: preventive effects of anti-oxidant agents.
Environ. Toxicol. Pharmacol. 12, p37-42 (2002)
24) M.Kakimoto, T.Inoguchi, T.Sonta, H.Y.Yu, M.Imamura, T.Etoh, T.Hashimoto and H.Nawata:
Accumulation of 8-hydroxy-2¡¦deoxyguanosine and mitochondrial DNA deletion in kidney of diabetic rats.
Diabetes 51, p1588-1595 (2002)
25) Takane, Naoyuki Sugano, Hiroyasu Iwasaki, Yoshihiro Iwano, Noritaka Shimizu and Koichi Ito:
New biomarker evidence of oxidative DNA damage in whole saliva from clinically healthy and periodontally diseased individuals.
J.Periodontol 73(5), p551-554 (2002)
26) Kayoko Shimoi, Hiroshi Kasai, Naoko Yokota, Shinya Toyokuni and Naohide Kinae:
Comparison between high-performance liquid chromatography and enzyme-linked immunosorbent assay for the determination of 8-hydroxy-2¡¦deoxyguanosine in human urine.
Cancer Epidemiol. Biomarkers & Prevention 11 p767-770 (2002)
27) Ha Won Kim, Akira Murakami, Marshall V Williams and Hajime Ohigashi:
Mutagenicity of reactive oxygen and nitrogen species as detected by co-culture of activated inflammatory leukocytes and AS52 cells.
Carcinogenesis 24(2), p235-241 (2003)
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28) Hirokazu Tsukahara, Rumiko Shibata, Yusei Ohshima, Yukiko Todoroki, Shuko Sato, Naoko Ohta, Masahiro Hiraoka, Akira Yoshida, Sankei Nishima, Mitsufumi Mayumi:
Oxidative stress and altered antioxidant defenses in children with acute exacerbation of atopic dermatitis. Life Sciences 72, p2509-2516(2003)
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29) Hirokazu Tsukahara, Mi-Zu Jiang, Naoko Ohta, Shuko Sato, Satoshi Tamura, Masahiro Hiraoka, Masayuki Maeda, Mitsufumi Mayumi:
Oxidative stress in neonates: Evaluation using specific biomarkers. Life Sciences 75, p933-938 (2004)
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30) Nagayoshi Y, Kawano H, Hokamaki J, Miyamoto S, Kojima S, Shimomura H, Tsujita K, Sakamoto T, Yoshimura M, Ogawa H:
Urinary 8-hydroxy-2'-deoxyguanosine levels increase after reperfusion in acute myocardial infarction and may predict subsequent cardiac events.
Am J Cardiol. 95(4), p514-517 (2005)
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31) Yutaka Otsuji, Eiji Kuwahara, Keiko Yuge, Goichi Yotsumoto, Takayuki Ueno, Kenichi Nakashiki, Shuichi Hamasaki, Sadatoshi Biro, Shinichi Minagoe, Robert A. Levine, Ryuzo Sakata, and Chuwa Tei:
Relation of Aneurysmectomy in Patients With Advanced Left Ventricular Remodeling to Postoperative Left Ventricular Filling Pressure, Redilatation With Ischemic Mitral Regurgitation.
Am J Cardiol 95, p517-521 (2005)
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32) Someya T, Kaneko K, Yamada T, Yamashiro Y.:
Effect of a novel free radical scavenger, edaravone, on puromycin aminonucleoside induced nephrosis in rats.
Pediatr Nephrol.20(10),p1430-1434(2005)
¥é¥Ã¥È¡ÊWistar-Kyoto rat¡Ë¤Ëpuromycin-aminonucleoside (PAN) ÅêÍ¿¤·¡¢¹³»À²½ºÞ¥¨¥À¥é¥Ü¥ó¡ÊEDA¡Ë¤Î¸ú²Ì¤ò¸¡¾Ú¡£ ¥¨¥À¥é¥Ü¥óÅêÍ¿·²¤ÎÇ¢Ãæ8-OH£äG¤Ï¥¨¥À¥é¥Ü¥óÈóÅêÍ¿·²¤ËÈæ¤ÙÄãÃͤò¼¨¤·¤Þ¤¹¡£
33) Morillas-Ruiz J, Zafrilla P, Almar M, Cuevas MJ, Lopez FJ, Abellan P, Villegas JA, Gonzalez-Gallego J:
The effects of an antioxidant-supplemented beverage on exercise-induced oxidative stress: results from a placebo-controlled double-blind study in cyclists
Eur J Appl Physiol 31,p1-7 (2005)
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34) Reiko Nagasaka, Nobuaki Okamoto, Hideki Ushio:
Effects of caloric restriction on post-spawning death of ayu.
Exp Gerontol 40, p556-561(2005)
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35) Hirokazu Tsukahara, Takeshi Sugaya, Kazuyo Hayakawa, Yukiko Mori, Masahiro Hiraoka, Atsuko Hata, Mitsufumi Mayumi: Quantification of L-type fatty acid binding protein in the urine of preterm neonates. Early Human Development 81, p643-646 (2005)
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36) Michael J Forlenza and Gregory E Miller: Increased serum levels of 8-hydroxy-2'-deoxyguanosine in clinical depression. Psychosomat Med 68, p1-7 (2006)
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37) Watanabe E, Matsuda N, Shiga T, Kajimoto K, Ajiro Y, Kawarai H, Kasanuki H, Kawana M:
Significance of 8-hydroxy-2'-deoxyguanosine levels in patients with idiopathic dilated cardiomyopathy.
J Card Fail 12(7),p527-532(2006) (Journal of cardiac failure)
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38) Shiihara T, Kato M, Ichiyama T, Takahashi Y, Tanuma N, Miyata R, Hayasaka K:
Acute encephalopathy with refractory status epilepticus: Bilateral mesial temporal and claustral lesions, associated with a peripheral marker of oxidative DNA damage
J Neurol Sci 250(1-2),p159-161(2006)
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39) Ikue Hata, Masayuki Kaji,Satoko Hirano, Yosuke Shigematsu, Hirokazu Tsukahara, and Mitsufumi Mayumi: Urinary oxidative stress markers in young patients with type 1 diabetes. Pediatrics International 48, p58-61 (2006)
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40) Roberto Cangemi, Francesco Angelico, Lorenzo Loffredo, Maria Del Ben, Pasquale Pignatelli, Alessandra Martini and Francesco Violi:
Oxidative stress-mediated arterial dysfunction in patients with metabolic syndrome: Effect of ascorbic acid.
Free Radical Biology and Medicine 43(5), p853-859 (2007)
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41) Tomasz Dziaman, Daniel Gackowski, Rafal Rozalski, Agnieszka Siomek, Jaroslaw Szulczynski, Romuald Zabielski, Ryszard Olinski:
Urinary excretion rates of 8-oxoGua and 8-oxodG and antioxidant vitamins level as a measure of oxidative status in healthy, full-term newborns.
Free Radical Research, 41(9), p997-1004(2007)
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42) Olga Espinosa, Jorge Jimenez-Almazan, Felipe J. Chaves, M. Carmen Tormos, Sonia Clapes, Antonio Iradi, Amparo Salvador, Marta Fandos, Josep Redon, Guillermo T. Saez:
Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxo-dG), a reliable oxidative stress marker in hypertension.
Free Radical Research 41(5), p546-554 (2007)
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43) Parul R Patel, Ruth J Bevan, Nalini MIstry, Joseph Lunec:
Evidence of oligonucleotides containing 8-hydroxy-2'-deoxyguanosine in human urine.
Free Radical Biol Med 42, p552-558(2007)
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44) Tsukahara H: Biomarkers for oxidative stress: clinical application in pediatric medicine. Curr Med Chem 14(3), p339-351 (2007)
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45) Nakano M, Onodera A, Saito E, Tanabe M, Yajima K, Takahashi J, Chuyen NV: Effect of Astaxanthin in Combination with alpha-Tocopherol or Ascorbic Acid against Oxidative Damage in Diabetic ODS Rats. J Nutr Sci Vitaminol (Tokyo). 54(4)p329-334 (2008)
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46) Ogawa S, Mori T, Nako K, Ito S: Combination therapy with renin-angiotensin system inhibitors and the calcium channel blocker azelnidipine decreases plasma inflammatory markers and urinary oxidative stress markers in patients with diabetic nephropathy. Hypertens Res 31(6), p1147-1155(2008)
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47) Yasuda M, Ide H, Furuya K, Yoshii T, Nishio K, Saito K, Isotani S, Kamiyama Y, Muto S, Horie S: Salivary 8-OHdG: a useful biomarker for predicting severe ED and hypogonadism. J Sex Med 5(6),p1482-1491(2008)
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48) Tamura H, Takasaki A, Miwa I, Taniguchi K, Maekawa R, Asada H, Taketani T, Matsuoka A, Yamagata Y, Shimamura K, Morioka H, Ishikawa H, Reiter RJ, Sugino N: Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate. J Pineal Res 44(3), p280-287(2008)
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49) Sakamoto Y, Ishikawa T, Kondo Y, Yamaguchi K, Fujisawa M: The assessment of oxidative stress in infertile patients with varicocele. BJU Int 101(12), p1547-1552(2008)
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50) Tanuma N, Miyata R, Hayashi M, Uchiyama A, Kurata K: Oxidative stress as a biomarker of respiratory disturbance in patients with severe motor and intellectual disabilities. Brain Dev 30(6), p402-409(2008)
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51) Kageyama Y, Takahashi M, Nagafusa T, Torikai E, Nagano A: Etanercept reduces the oxidative stress marker levels in patients with rheumatoid arthritis. Rheumatol Int 28(3), p245-251(2008)
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52) Fujimoto M, Tsuneyama K, Kainuma M, Sekiya N, Goto H, Takano Y, Terasawa K, Selmi C, Gershwin ME, Shimada Y: Evidence-based efficacy of Kampo formulas in a model of non alcoholic fatty liver. Exp Biol Med (Maywood) 233(3),p328-337(2008)
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53) Chen CM, Liu JL, Wu YR, Chen YC, Cheng HS, Cheng ML, Chiu DT: Increased oxidative damage in peripheral blood correlates with severity of Parkinson's disease. Neurobiol Dis 2008 Dec 9.(in press)
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54) Yano T, Shoji F, Baba H, Koga T, Shiraishi T, Orita H, Kohno H: Significance of the urinary 8-OHdG level as an oxidative stress marker in lung cancer patients. Lung Cancer 63(1) p111-114 (2009)
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55) Yee Ting Wong, Jan Gruber, Andrew M. Jenner, Mary Pei-Ern Ng, Runsheng Ruan, and Francis Eng Hock Tay: Elevation of oxidative-damage biomarkers during aging in F2 hybrid mice: Protection by chronic oral intake of resveratrol. Free Rad Biol Med 46(6), p799-809(2009)
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56) Haixiang Su, Mervyn Gornitsky, Ana M. Velly, Hanling Yu, Michael Benarroch and Hyman M. Schipper: Salivary DNA, lipid, and protein oxidation in nonsmokers with periodontal disease. Free Radical Biology and Medicine 46(7), p914-921 (2009)
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57) Hironori Nagasaka, Yoshiyuki Okano, Hirokazu Tsukahara, Yosuke Shigematsu, Toru Momoi, Junko Yorifuji, Takashi Miida, Toshihiro Ohura, Keiko Kobayashi, Takeyori Saheki, Kenichi Hirano, Masaki Takayanagi, Tohru Yorifuji:
Sustaining hypercitrullinemia, hypercholesterolemia and augmented oxidative stress in Japanese children with aspartate/glutamate carrier isoform 2-citrin-deficiency even during the silent period. Molecular Genetics and Metabolism 97, p21-26(2009)
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58) Higuchi A, Takahashi K, Hirashima M, Kawakita T, Tsubota K: Selenoprotein P Controls Oxidative Stress in Cornea. PLoS ONE 5(3) e9911 (2010)
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59) Anna Szaflarska-Popawska, Agnieszka Siomek, Mieczysawa Czerwionka-Szaflarska, Daniel Gackowski, Rafa Rozaliski, Jolanta Guz, Anna Szpila, Ewelina Zarakowska and Ryszard Olinski:
Oxidatively Damaged DNA/Oxidative Stress in Children with Celiac Disease. Cancer Epidemiol Biomarkers Prev 19(8), p1960-1965(2010)
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Altered metabolisms of mediators controlling vascular function and enhanced oxidative stress in asymptomatic children with congenital portosystemic venous shunt. Metabolism Clinical and Experimental 59, p107-113(2010)
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61) Masashi Kato, Machiko Iida, Yuji Goto, Takaaki Kondo, and Ichiro Yajima:
Sunlight Exposure Mediated DNA Damage in Young Adults. Cancer Epidemiol Biomarkers Prev 20(8), p1622-1628 (2011)
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62) Elmarakby AA, Faulkner J, Baban B, Sullivan JC:
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Int J Hypertens (2012), Article ID 957235,doi:10.1155/2012/957235
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63) La Sala L, Cattaneo M, De Nigris V, Pujadas G, Testa R, Bonfigli AR, Genovese S, Ceriello A:
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64) Wang DH, Yamada A, Miyanaga M:
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